Malaria has long plagued humanity, with cases (or at least what we assume are cases based on symptoms) reported as far back as 2700 BCE. Caused by a mosquito-transmitted parasite (something humanity didn’t realize until the late 1800s), malaria is a serious and sometimes fatal disease that presents with symptoms including high fevers, chills, and flu-like symptoms. It also ravaged much of the known world, with cases occurring everywhere from southern Europe to Eastern China, killing tens of millions in the process.