In 2018-2019, the US FDA detected cancer-causing impurities in a group of drugs that control blood pressure, prompting manufacturers and distributors to recall their products. In its most basic form, nitrosamines consist of two linked nitrogen atoms with two carbon and oxygen at the opposite end of the nitrogen bridge. With such a simple structure derived from a vulnerable amine, nitrosamines have the potential to form and stay — but how likely? Out in the Journal of Pharmaceutical Science, a group of researchers assessed the prevalence of nitrosamines formation through a computational study.