Nurses are at risk of poor sleep health and may be an important target population for sleep interventions. However, little is known about the factors predicting preferences for different sleep intervention types or deliveries. This current study examined the relationship between diverse factors (e.g., sociodemographics, sleep hygiene knowledge, personality) and preferences for various sleep interventions. The data was collected from 86 outpatient nurses. Participants provided their sociodemographic information and completed questionnaires assessing their personality traits, sleep hygiene knowledge and preferences for sleep intervention types and deliveries. Nearly all participants were interested in participating in a sleep intervention (99%). The preferred sleep intervention type among respondents was mindfulness-based training (74%), while an online format (88%) was the most favored delivery method. Those with lower incomes and lower agreeableness were associated with endorsing sleep hygiene education more frequently. Nurses who had more than one child, provided sleep hygiene tips to patients, and demonstrated higher levels of openness and agency were inclined to endorse mindfulness-based training. For sleep intervention delivery, nurses who worked longer hours and nurses who did not provide sleep hygiene tips to patients favored group meetings more highly. Being White Hispanic or a person of color was associated with a higher endorsement of one-on-one meetings. Finally, nurses of a younger age and being a single child parent were associated with a higher endorsement for an online format delivery of sleep interventions. Findings from this study may help inform the planning, recruitment, and implementation of future interventions aimed to improve sleep health in nurses, and further, in other vulnerable healthcare workers.